Michela Bosetti graduated with a degree in Pharmacy, specialising in Toxicology, PhD in “Molecular Medicine” and a Master in Biomaterials. From 2001 research-worker SSD BIO-16 Human Anatomy, actually qualified as Full Professor.
The research activity is aimed at the in vitro study and the development of new biomaterials and therapies for
biomedical use and tissue regeneration with particular attention to bone and cartilage tissue and wound healing:
- The use of micro-fragmented adipose tissue (lipoaspirate) as a natural autologous scaffold rich in stem cells in the regeneration of tissue defects;
- Action of growth factors and molecules extracted from food industry waste on mature cells of bone tissue (osteoblasts, osteoclasts and chondrocytes) and on the differentiation of mesenchymal stem cells (obtained from bone marrow and adipose tissue);
- Development of injectable scaffolds active in tissue regeneration at the site of damage (gel-medicated with growth factors or siRNA-nanoparticles or natural molecules);
- Role of mechanical stress and inflammatory factors on the differentiation and activation of bone cells: formation of bone tissue in the arterial wall;
- Cytotoxicity, Genotoxicity and Biocompatibility of materials used in Surgery;
- Inflammatory activity of biomaterials (Chemiluminescence, cytokine release, complement activation, MIFtest, SEM, TEM).
Co-author of more than 100 scientific publications (78 in international journals with impact factor), Scopus h-index 24,
Citations 2300. ORCID Profile https://orcid.org/0000-0002-3682-8702